Description
Area: Medical Genetics/Genomics/C. elegans
Duration: 1 year with possibility of extension
Start Date: Negotiable
Salary: Negotiable
The Department of Biochemistry & Molecular Biology in the Cumming School of Medicine at the University of Calgary is accepting applications for a Postdoctoral Scholar focused on high throughput identification of genetic modifiers, genetic interactions, using a model organism, Caenorhabditis elegans.
The available position is part of the multidisciplinary research program in the Tarailo-Graovac group which combines human and model organism (Caenorhabditis elegans) genomics and traditional molecular genetics approaches to understand genetic modifiers of rare human disease with focus on diseases related to centriole biogenesis deficiencies. We also study diseases related to deficiencies in mRNA biogenesis. We utilize high throughput genetic screens, whole genome sequencing, transcriptome sequencing and CRISPR/Cas9 knock-out and knock-in methods to better understand human disease.
We are looking for a creative and highly motivated postdoctoral fellow with strong interest in genetic interactions, human disease, penetrance/expressivity, phenotype-genotype correlations and deeper understanding of the mechanisms associated with proper centriole function or mechanisms related to proper mRNA biogenesis. The ideal candidate will have expertise in C. elegans molecular techniques and a passion for research.
Job Description:
- Keeping up-to-date with scientific advances (e.g. relevant literature review, scientific meetings)
- Designing projects and experiments
- Utilizing CRISPR/Cas9 procedures in C. elegans to model human disease
- Compiling, analyzing and interpreting diverse sets of data (e.g. phenomics, genomics, transcriptomics)
- Writing study reports, manuscripts
- Communicating results: conference presentations, collaborators nationally and internationally
- Validating bioinformatics discoveries experimentally
- Providing supervision and mentorship to graduate and undergraduate students
- Reporting to Dr. Tarailo-Graovac and the team on the progress during regular individual and lab meetings
Qualifications:
- PhD, with 2 years or less of post-PhD research
- Demonstrated excellence (e.g. peer reviewed publications, relevant resources or alternative forms of research output)
- Knowledge/interest in model organisms, C. elegans in particular
- Extensive knowledge of genetics
- Experience working with animal models of disease
- Experience in molecular genetics
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The candidate is expected to show
- Drive and enthusiasm to both lead and work as a member of a team
- Creativity, initiative and good judgment for multi-tasking in a deadline oriented environment
- Effective oral and written communication, analytical, and interpersonal skills
- Excellent organizational skills and ability to learn new skills quickly
- Enthusiasm for highly interdisciplinary research and drive to explore emerging techniques
- Accuracy and attention to detail
Application Details:
Interested applicants should submit a cover letter with research interests, statement on their future goals, and fit with the group¿s research focus, curriculum vitae, and the names of three referees willing to provide letters of reference to Dr. Maja Tarailo-Graovac at [email protected]. Only shortlisted candidates will be contacted. The position will be open until suitable candidate is identified.
The terms and conditions of employment are covered under the UCalgary and PDAC Collective Agreement. To find out more about postdoctoral scholar program at the University of Calgary visit our Postdocs website.
To learn more about postdoctoral scholar opportunities at the University of Calgary, view our Postdoc Careers website.
About the University of Calgary
UCalgary is Canada's entrepreneurial university, located in Canada's most enterprising city. It is a top research university and one of the highest-ranked universities of its age. Founded in 1966, its 36,000 students experience an innovative learning environment, made rich by research, hands-on experiences and entrepreneurial thinking. It is Canada's leader in the creation of start-ups. Start something today at the University of Calgary. For more information, visit ucalgary.ca.
About Calgary, Alberta
Calgary is one of the world's cleanest cities and has been named one of the world's most livable cities for years. Calgary is a city of leaders' in business, community, philanthropy and volunteerism. Calgarians benefit from the strongest economy in the nation and enjoy more days of sunshine per year than any other major Canadian city. Calgary is less than an hour's drive from the Rocky Mountains and boasts the most extensive urban pathway and bikeway network in North America.
The University of Calgary has launched an institution-wide Indigenous Strategy committing to creating a rich, vibrant, and culturally competent campus that welcomes and supports Indigenous Peoples, encourages Indigenous community partnerships, is inclusive of Indigenous perspectives in all that we do.
As an equitable and inclusive employer, the University of Calgary recognizes that a diverse staff/faculty benefits and enriches the work, learning and research experiences of the entire campus and greater community. We are committed to removing barriers that have been historically encountered by some people in our society. We strive to recruit individuals who will further enhance our diversity and will support their academic and professional success while they are here. In particular, we encourage members of the designated groups (women, Indigenous peoples, persons with disabilities, members of visible/racialized minorities, and diverse sexual orientation and gender identities) to apply. To ensure a fair and equitable assessment, we offer accommodation at any stage during the recruitment process to applicants with disabilities. Questions regarding [diversity] EDI at UCalgary can be sent to the Office of Institutional Commitments ([email protected]) and requests for accommodations can be sent to Human Resources ([email protected]).
